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Nutrition, Substance Abuse, & the Heart

In general, the research shows improving overall nutritional status will help reduce cravings & relapse. I include specifics of my own recommendations in many other nutrition-related posts. The short list of nutrients below can help certain Substance Use Disorders & help prevent &/or treat certain Heart diseases. I have not included doses. These health problems are complex, individual, & many patients are on medications, which can have interactions. This kind of targeted supplementation needs to be done by a health professional. Your local #naturopathicdoctor is well-qualified to do this. This isn’t a full list & is only intended as a resource for you to take to your healthcare practitioner: Vitamin C 💘Atherosclerosis (Build-up of hardened fat in an artery) 💘Ischemic heart disease (loss of blood to heart muscle causing death of muscle cells, often leads to heart attack) 💘Hypertension (constant high blood pressure) 💘Thrombophlebitis (Painful inflammation of a blood vessel) ☣Opioid addiction

Niacin (B3) 💘Atherosclerosis 💘Ischemic heart disease 💘High triglycerides ☣Alcohol use disorder ☣Opioid addiction Folic acid (B9) 💘Congenital heart defects (occur during fetal development) 💘Congestive Heart Failure (pumping problems caused when fluid builds up around the heart) 💘Stroke (blood clot lodged in a brain vessel stopping blood flow (ischemic), or caused the vessel in the brain to burst (hemorrhagic)) 💘Coronary heart disease (atherosclerosis) 💘Pre-eclampsia (pregnancy complication of high blood pressure & signs of damage to another organ) ☣Alcohol use disorder Cyanocobalamin (B12, in SUD’s I prefer methyl-B12) 💘Atherosclerosis 💘Hyperhomocysteinemia (High homocysteine; contributing factor to many heart/vessel problems) 💘CHF 💘Congenital heart defects ☣Alcohol use disorder Magnesium 💘OMG, so many heart benefits ☣Opioid addiction ☣Cocaine addiction (but, give w potassium)

Fermented foods & Probiotics 💘Hypertension ☣Opioid addiction ☣Alcohol use disorder

Omega-3 fatty acids 💘Again, so many heart benefits ☣Opioid addiction ☣Alcohol use disorder

Thiamine (B1) 💘Heart Failure ☣Alcohol use disorder

n-Acetyl-Cysteine 💘Ischemic heart disease 💘Post-MI recovery 💘Particulate matter induced heart damage (like from wildfires or other air pollution) ☣Cannabis addiction ☣Gambling addiction ☣Methamphetamine addiction ☣Tobacco addiction I hope this gives you & your doc a good starting point. Remember, nutrition is just one aspect in recovering from an SUD &/or a heart/vessel condition. References

  • Gaby, A.(2017). Nutritional Medicine, 2nd ed. Fritz Perlberg Publishing: Concord, NH.

  • Polytarchou K, Dimitroglou Y, Varvarousis D, et al. Methylmalonic Acid and Vitamin B12 in Patients with Heart Failure [published online ahead of print, 2019 Nov 15]. Hellenic J Cardiol. 2019;S1109-9666(19)30286-6. doi:10.1016/j.hjc.2019.10.010

  • Şanlier N, Gökcen BB, Sezgin AC. Health benefits of fermented foods. Crit Rev Food Sci Nutr. 2019;59(3):506–527. doi:10.1080/10408398.2017.1383355

  • Hakimian JK, Dong TS, Barahona JA, et al. Dietary Supplementation with Omega-3 Polyunsaturated Fatty Acids Reduces Opioid-Seeking Behaviors and Alters the Gut Microbiome. Nutrients. 2019;11(8):1900. Published 2019 Aug 14. doi:10.3390/nu11081900

  • Poulose SM, Miller MG, Scott T, Shukitt-Hale B. Nutritional Factors Affecting Adult Neurogenesis and Cognitive Function. Adv Nutr. 2017;8(6):804–811. Published 2017 Nov 15. doi:10.3945/an.117.016261

  • Elizabeth KE, Praveen SL, Preethi NR, Jissa VT, Pillai MR. Folate, vitamin B12, homocysteine and polymorphisms in folate metabolizing genes in children with congenital heart disease and their mothers. Eur J Clin Nutr. 2017;71(12):1437–1441. doi:10.1038/ejcn.2017.135

  • Reece AS, Hulse GK. What are the characteristics of vitamin D metabolism in opioid dependence? An exploratory longitudinal study in Australian primary care. BMJ Open. 2018;8(1):e016806. Published 2018 Jan 13. doi:10.1136/bmjopen-2017-016806

  • Fayemi PO, Muchenje V, Yetim H, Ahhmed A. Targeting the pains of food insecurity and malnutrition among internally displaced persons with nutrient synergy and analgesics in organ meat. Food Res Int. 2018;104:48–58. doi:10.1016/j.foodres.2016.11.038

  • Alexa T, Marza A, Voloseniuc T, Tamba B. Enhanced analgesic effects of tramadol and common trace element coadministration in mice. J Neurosci Res. 2015;93(10):1534–1541. doi:10.1002/jnr.23609

  • Sebastiani G, Borrás-Novell C, Casanova MA, et al. The Effects of Alcohol and Drugs of Abuse on Maternal Nutritional Profile during Pregnancy. Nutrients. 2018;10(8):1008. Published 2018 Aug 2. doi:10.3390/nu10081008

  • Jeynes KD, Gibson EL. The importance of nutrition in aiding recovery from substance use disorders: A review. Drug Alcohol Depend. 2017;179:229–239. doi:10.1016/j.drugalcdep.2017.07.006

  • Hamel J, Logigian EL. Acute nutritional axonal neuropathy. Muscle Nerve. 2018;57(1):33–39. doi:10.1002/mus.25702

  • Gautron MA, Questel F, Lejoyeux M, Bellivier F, Vorspan F. Nutritional Status During Inpatient Alcohol Detoxification. Alcohol Alcohol. 2018;53(1):64–70. doi:10.1093/alcalc/agx086

  • Liu D, Ke Z, Luo J. Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy. Mol Neurobiol. 2017;54(7):5440–5448. doi:10.1007/s12035-016-0079-9

  • Narasimha VL, Ganesh S, Reddy S, et al. Pellagra and Alcohol Dependence Syndrome: Findings From a Tertiary Care Addiction Treatment Centre in India. Alcohol Alcohol. 2019;54(2):148–151. doi:10.1093/alcalc/agz004

  • Frank LL. Thiamin in Clinical Practice. JPEN J Parenter Enteral Nutr. 2015;39(5):503–520. doi:10.1177/0148607114565245

  • Lennox RD, Cecchini-Sternquist M. Safety and tolerability of sauna detoxification for the protracted withdrawal symptoms of substance abuse. J Int Med Res. 2018;46(11):4480–4499. doi:10.1177/0300060518779314

  • Barr T, Sureshchandra S, Ruegger P, et al. Concurrent gut transcriptome and microbiota profiling following chronic ethanol consumption in nonhuman primates. Gut Microbes. 2018;9(4):338–356. doi:10.1080/19490976.2018.1441663


  • Mao B, Qiu J, Zhao N, et al. Maternal folic acid supplementation and dietary folate intake and congenital heart defects. PLoS One. 2017;12(11):e0187996. Published 2017 Nov 16. doi:10.1371/journal.pone.0187996

  • Peng Y, Ou BQ, Li HH, et al. Synergistic Effect of Atorvastatin and Folic Acid on Cardiac Function and Ventricular Remodeling in Chronic Heart Failure Patients with Hyperhomocysteinemia. Med Sci Monit. 2018;24:3744–3751. Published 2018 Jun 4. doi:10.12659/MSM.906893

  • Wen SW, White RR, Rybak N, et al. Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (FACT): double blind, phase III, randomised controlled, international, multicentre trial. BMJ. 2018;362:k3478. Published 2018 Sep 12. doi:10.1136/bmj.k3478


  • Bartekova M, Barancik M, Ferenczyova K, Dhalla NS. Beneficial Effects of N-acetylcysteine and N-mercaptopropionylglycine on Ischemia Reperfusion Injury in the Heart. Curr Med Chem. 2018;25(3):355–366. doi:10.2174/0929867324666170608111917

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